Open AccessRisk stratification and pattern of cardiotoxicity in pediatric Ewing sarcoma
Author(s) -
E Moussa,
Manal Zamzam,
Ayman H. Kamel,
Zeinab Salah,
Iman Attia,
Lina Gaber,
Ranin Soliman,
Sameera Ezzat
Publication year - 2017
Publication title -
journal of egyptian national cancer institute/journal of the egyptian national cancer institute
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.398
H-Index - 22
eISSN - 2589-0409
pISSN - 1110-0362
DOI - 10.1016/j.jnci.2016.12.001
Subject(s) - medicine , cardiotoxicity , risk stratification , ewing's sarcoma , sarcoma , stratification (seeds) , oncology , cardiology , chemotherapy , pathology , seed dormancy , botany , germination , dormancy , biology
Anthracycline chemotherapy contributes to improved outcomes in Ewing sarcoma; however, the most feared complication is cardiotoxicity. Echocardiograms were routinely used to monitor cardiac function after anthracycline treatment. Nevertheless, indices chosen to assess cardiac toxicity vary significantly among different centers, and no uniform protocol has been accepted as ideal.