Open AccessAssessment of leptin and resistin levels in non-obese multiple myeloma patients and their relation with Ig level and disease stage
Author(s) -
Noha E. Esheba,
Abeer Shahba,
Ola El Shora
Publication year - 2014
Publication title -
journal of egyptian national cancer institute/journal of the egyptian national cancer institute
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.398
H-Index - 22
eISSN - 2589-0409
pISSN - 1110-0362
DOI - 10.1016/j.jnci.2014.02.002
Subject(s) - resistin , leptin , medicine , multiple myeloma , adipokine , stage (stratigraphy) , endocrinology , pathogenesis , disease , cancer , gastroenterology , obesity , paleontology , biology
Multiple myeloma (MM) accounts for approximately 0.8% of all cancer diagnoses and 0.9% of cancer deaths. Leptin receptors were expressed on CD34(+) cells. Resistin receptors were expressed on inflammatory cells and pro-inflammatory cytokines increase the expression of resistin on monocytes.