Open AccessLow expression of the K280N TNNT2 mutation is sufficient to increase basal myofilament activation in human hypertrophy cardiomyopathy
Author(s) -
Vasco Sequeira,
Lili Wang,
Paul J.M. Wijnker,
Kyungsoo Kim,
José R. Pinto,
Cristobal G. dos Remedios,
Charles Redwood,
Björn C. Knollmann,
Jolanda van der Velden
Publication year - 2022
Publication title -
journal of molecular and cellular cardiology plus
Language(s) - English
Resource type - Journals
ISSN - 2772-9761
DOI - 10.1016/j.jmccpl.2022.100007
Subject(s) - myofilament , troponin complex , mutation , medicine , hypertrophic cardiomyopathy , troponin t , endocrinology , biology , myocyte , troponin , gene , genetics , myocardial infarction
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