Genetic diversity of MERS-CoV spike protein gene in Saudi Arabia
Author(s) -
Sayed Sartaj Sohrab,
Esam I. Azhar
Publication year - 2019
Publication title -
journal of infection and public health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.983
H-Index - 35
eISSN - 1876-035X
pISSN - 1876-0341
DOI - 10.1016/j.jiph.2019.11.007
Subject(s) - phylogenetic tree , genetic diversity , gene , biology , phylogenetics , genetics , outbreak , spike protein , middle east respiratory syndrome , virology , disease , covid-19 , medicine , infectious disease (medical specialty) , population , environmental health , pathology
Middle East respiratory syndrome coronavirus (MERS-CoV) was primarily detected in 2012 and still causing disease in human and camel. Camel and bats have been identified as a potential source of virus for disease spread to human. Although, significant information related to MERS-CoV disease, spread, infection, epidemiology, clinical features have been published, A little information is available on the sequence diversity of Spike protein gene. The Spike protein gene plays a significant role in virus attachment to host cells. Recently, the information about recombinant MERS-CoV has been published. So, this work was designed to identify the emergence of any another recombinant virus in Jeddah, Saudi Arabia.
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