Open AccessInnate immune response analysis in COVID-19 and kawasaki disease reveals MIS-C predictors
Author(s) -
Chin-An Yang,
YaLing Huang,
BorLuen Chiang
Publication year - 2021
Publication title -
journal of the formosan medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.708
H-Index - 54
eISSN - 1876-0821
pISSN - 0929-6646
DOI - 10.1016/j.jfma.2021.06.009
Subject(s) - innate immune system , immunology , transcriptome , cd14 , immune system , tlr2 , medicine , biology , gene , genetics , gene expression
The association between dysregulated innate immune responses seen in Kawasaki disease (KD) with predisposition to Kawasaki-like multisystem inflammatory syndrome in children (MIS-C) remains unclear. We aimed to compare the innate immunity transcriptome signature between COVID-19 and KD, and to analyze the interactions of these molecules with genes known to predispose to KD.
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