Determination of ketoprofen based on its quenching effect in the fluorescence of quantum dots | Zendy

Lucía MolinaGarcía | Zendy; João L.M. Santos | Zendy; A. RuizMedina | Zendy; Eulogio J. LlorentMartínez | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Determination of ketoprofen based on its quenching effect in the fluorescence of quantum dots

Author(s) -

Lucía MolinaGarcía,

João L.M. Santos,

A. RuizMedina,

Eulogio J. LlorentMartínez

Publication year - 2013

Publication title -

journal of food and drug analysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.277

H-Index - 54

eISSN - 2224-6614

pISSN - 1021-9498

DOI - 10.1016/j.jfda.2013.09.007

Subject(s) - ketoprofen , quantum dot , quenching (fluorescence) , fluorescence , photochemistry , chemistry , materials science , nanotechnology , chromatography , physics , optics

Ketoprofen is a potent nonsteroidal anti-inflammatory drug used for the treatment of inflammatory diseases and musculoskeletal injuries. Taking into account the increasing consumption of this drug, it is important to develop a rapid, easy, and reliable analytical strategy for its quality control. In this work, we present a novel method for ketoprofen determination, based on its quenching effect produced in the fluorescence of CdTe quantum dots modified by mercaptopropionic acid. Under optimized conditions, the method was linear in the range of 7.5–100 μg/mL, with a detection limit of 2.3 μg/mL and relative standard deviations lower than 2%. It was applied to the determination of ketoprofen in pharmaceutical formulations, obtaining results in good agreement with those provided by the manufacturer

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research