Successful use of combined corticosteroids and rituximab in a patient with refractory cutaneous polyarteritis nodosa | Zendy

Ibrahim A. Al-Homood | Zendy; Mohammad A. Aljahlan | Zendy

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Successful use of combined corticosteroids and rituximab in a patient with refractory cutaneous polyarteritis nodosa

Author(s) -

Ibrahim A. Al-Homood,

Mohammad A. Aljahlan

Publication year - 2016

Publication title -

journal of dermatology and dermatologic surgery

Language(s) - English

Resource type - Journals

eISSN - 2352-2429

pISSN - 2352-2410

DOI - 10.1016/j.jdds.2016.05.004

Subject(s) - polyarteritis nodosa , rituximab , medicine , refractory (planetary science) , dermatology , vasculitis , immunology , antibody , biology , disease , astrobiology

Cutaneous polyarteritis nodosa is a rare subtype of polyarteritis nodosa that lacks significant internal organ involvement. It has a relapsing remitting nature and usually is less responsive to conventional treatments. We report a case of refractory cutaneous polyarteritis nodosa who failed three immunosuppressive therapies and three different biological agents. He was successfully treated with two rituximab 1000mg infusions with a good efficacy and tolerance. This case demonstrates the safety and efficacy of rituximab in treatment of refractory cutaneous polyarteritis nodosa

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