Open AccessSuccessful use of combined corticosteroids and rituximab in a patient with refractory cutaneous polyarteritis nodosa
Author(s) -
Ibrahim A. Al-Homood,
Mohammad A. Aljahlan
Publication year - 2017
Publication title -
journal of dermatology and dermatologic surgery
Language(s) - English
Resource type - Journals
eISSN - 2352-2429
pISSN - 2352-2410
DOI - 10.1016/j.jdds.2016.05.004
Subject(s) - medicine , polyarteritis nodosa , rituximab , refractory (planetary science) , dermatology , immunology , vasculitis , antibody , disease , astrobiology , physics
Cutaneous polyarteritis nodosa is a rare subtype of polyarteritis nodosa that lacks significant internal organ involvement. It has a relapsing remitting nature and usually is less responsive to conventional treatments. We report a case of refractory cutaneous polyarteritis nodosa who failed three immunosuppressive therapies and three different biological agents. He was successfully treated with two rituximab 1000mg infusions with a good efficacy and tolerance. This case demonstrates the safety and efficacy of rituximab in treatment of refractory cutaneous polyarteritis nodosa