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Importance of Myocardial Fibrosis in Functional Mitral Regurgitation
Author(s) -
Bernardo B.C. Lopes,
Deborah Kwon,
Dipan J. Shah,
John R. Lesser,
Vinayak Bapat,
Maurice EnriquezSarano,
Paul Sorajja,
João L. Cavalcante
Publication year - 2021
Publication title -
jacc. cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.79
H-Index - 120
eISSN - 1936-878X
pISSN - 1876-7591
DOI - 10.1016/j.jcmg.2020.10.027
Subject(s) - cardiology , risk stratification , functional mitral regurgitation , medicine , myocardial fibrosis , mitral regurgitation , cardiac magnetic resonance , fibrosis , magnetic resonance imaging , heart failure , radiology , ejection fraction
Functional mitral regurgitation (FMR) is a common and complex valve disease, in which severity and risk stratification is still a conundrum. Although risk increases with FMR severity, it is modulated by subjacent left ventricular (LV) disease. The extent of LV remodeling and dysfunction is traditionally evaluated by echocardiography, but a growing body of evidence shows that myocardial fibrosis (MF) assessment by cardiac magnetic resonance (CMR) may complement risk stratification and inform treatment decisions. This review summarizes the current knowledge on the comprehensive evaluation that CMR can provide for patients with FMR, in particular for the assessment of MF and its potential impact in clinical decision-making.

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