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Label-Free Visualization and Quantification of Biochemical Markers of Atherosclerotic Plaque Progression Using Intravascular Fluorescence Lifetime
Author(s) -
Julien Bec,
Deborah Vela,
Jennifer E. Phipps,
Michael Agung,
Jakob Unger,
Kenneth B. Margulies,
Jeffrey Southard,
L. Maximilian Buja,
Laura Marcu
Publication year - 2020
Publication title -
jacc. cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.79
H-Index - 120
eISSN - 1936-878X
pISSN - 1876-7591
DOI - 10.1016/j.jcmg.2020.10.004
Subject(s) - autofluorescence , multispectral image , fluorescence lifetime imaging microscopy , intravascular ultrasound , biomedical engineering , fluorescence , pathology , spectral signature , receiver operating characteristic , fibrous cap , spectral imaging , atheroma , materials science , in vivo , medicine , radiology , optics , computer science , biology , artificial intelligence , physics , quantum mechanics , microbiology and biotechnology , psychiatry
This study aimed to systematically investigate whether plaque autofluorescence properties assessed with intravascular fluorescence lifetime imaging (FLIm) can provide qualitative and quantitative information about intimal composition and improve the characterization of atherosclerosis lesions.

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