Regional Distribution of Fluorine-18-Flubrobenguane and Carbon-11-Hydroxyephedrine for Cardiac PET Imaging of Sympathetic Innervation
Author(s) -
Jason G.E. Zelt,
Deron Britt,
Braeden A. Mair,
Benjamin H. Rotstein,
Sarah Quigley,
Olga Walter,
Linda Garrard,
Simon P. Robinson,
Lisa Mielniczuk,
Robert A. deKemp,
Rob Beanlands
Publication year - 2020
Publication title -
jacc. cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.79
H-Index - 120
eISSN - 1936-878X
pISSN - 1876-7591
DOI - 10.1016/j.jcmg.2020.09.026
Subject(s) - distribution (mathematics) , pet imaging , sympathetic nervous system , medicine , sympathetic innervation , cardiology , positron emission tomography , nuclear medicine , mathematics , blood pressure , mathematical analysis
The aim of this study was to investigate the regional distribution of novel 18 F-labeled positron emission tomographic (PET) tracer flubrobenguane (FBBG) (whose longer half-life could enable more widespread use) to assess myocardial presynaptic sympathetic nerve function in humans in comparison to [ 11 C]meta-hydroxyephedrine (HED).
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