Plasma ACE2 Activity Predicts Mortality in Aortic Stenosis and Is Associated With Severe Myocardial Fibrosis | Zendy

Jay Ramchand | Zendy; Sheila K. Patel | Zendy; Robert E. Kearney | Zendy; George Matalanis | Zendy; Omar Farouque | Zendy; Piyush Srivastava | Zendy; Louise M. Burrell | Zendy

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Plasma ACE2 Activity Predicts Mortality in Aortic Stenosis and Is Associated With Severe Myocardial Fibrosis

Author(s) -

Jay Ramchand,

Sheila K. Patel,

Robert E. Kearney,

George Matalanis,

Omar Farouque,

Piyush Srivastava,

Louise M. Burrell

Publication year - 2019

Publication title -

jacc. cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.79

H-Index - 120

eISSN - 1936-878X

pISSN - 1876-7591

DOI - 10.1016/j.jcmg.2019.09.005

Subject(s) - medicine , cardiology , myocardial fibrosis , stenosis , fibrosis , biomarker , heart failure , aortic valve stenosis , brain natriuretic peptide , biochemistry , chemistry

This study investigated the relationship between plasma angiotensin-converting enzyme 2 (ACE2) activity levels and the severity of stenosis and myocardial remodeling in patients with aortic stenosis (AS) and determined if plasma ACE2 levels offered incremental prognostic usefulness to predict all-cause mortality.

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