How to Image Cardiac Amyloidosis
Author(s) -
Sharmila Dorbala,
Sarah Cuddy,
Rodney H. Falk
Publication year - 2019
Publication title -
jacc. cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.79
H-Index - 120
eISSN - 1936-878X
pISSN - 1876-7591
DOI - 10.1016/j.jcmg.2019.07.015
Subject(s) - cardiac amyloidosis , transthyretin , amyloidosis , medicine , magnetic resonance imaging , stage (stratigraphy) , disease , amyloid (mycology) , cardiac magnetic resonance , cardiology , restrictive cardiomyopathy , heart failure , radiology , cardiomyopathy , pathology , paleontology , biology
Cardiac amyloidosis (CA) is one of the most rapidly progressive forms of heart disease, with a median survival from diagnosis, if untreated, ranging from <6 months for light chain amyloidosis to 3 to 5 years for transthyretin amyloidosis. Early diagnosis and accurate typing of CA are necessary for optimal management of these patients. Emerging novel disease modifying therapies increase the urgency to diagnose CA at an early stage and identify patients who may benefit from these life-saving therapies. The goal of this review is to provide a practical approach to echocardiography, cardiac magnetic resonance, and radionuclide imaging in patients with known or suspected CA.
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