Relative Apical Sparing of Myocardial Longitudinal Strain Is Explained by Regional Differences in Total Amyloid Mass Rather Than the Proportion of Amyloid Deposits
Author(s) -
Paco E. Bravo,
Kana Fujikura,
Marie Foley Kijewski,
Michael JeroschHerold,
Sophia Jacob,
Mohamed Samir El-Sady,
William Sticka,
Shipra Dubey,
Anthony P. Belanger,
MiAe Park,
Marcelo F. Di Carli,
Raymond Y. Kwong,
Rodney H. Falk,
Sharmila Dorbala
Publication year - 2018
Publication title -
jacc. cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.79
H-Index - 120
eISSN - 1936-878X
pISSN - 1876-7591
DOI - 10.1016/j.jcmg.2018.06.016
Subject(s) - cardiac amyloidosis , magnetic resonance imaging , extracellular fluid , amyloid (mycology) , positron emission tomography , apex (geometry) , nuclear medicine , extracellular , medicine , amyloidosis , cardiology , pathology , chemistry , anatomy , radiology , biochemistry
This study sought to test whether relative apical sparing (RELAPS) of left ventricular (LV) longitudinal strain (LS) in cardiac amyloidosis (CA) is explained by regional differences in markers of amyloid burden ( 18 F-florbetapir uptake by positron emission tomography [PET] and/or extracellular volume fraction [ECV] by cardiac magnetic resonance (CMR)].
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