OCT for the Identification of Vulnerable Plaque in Acute Coronary Syndrome | Zendy

Hannah Sinclair | Zendy; Christos V. Bourantas | Zendy; Alan Bagnall | Zendy; Gary S. Mintz | Zendy; Vijay Kunadian | Zendy

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OCT for the Identification of Vulnerable Plaque in Acute Coronary Syndrome

Author(s) -

Hannah Sinclair,

Christos V. Bourantas,

Alan Bagnall,

Gary S. Mintz,

Vijay Kunadian

Publication year - 2015

Publication title -

jacc. cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.79

H-Index - 120

eISSN - 1936-878X

pISSN - 1876-7591

DOI - 10.1016/j.jcmg.2014.12.005

Subject(s) - acute coronary syndrome , vulnerable plaque , optical coherence tomography , medicine , fibrous cap , intravascular ultrasound , modalities , cardiology , modality (human–computer interaction) , vulnerability (computing) , clinical practice , radiology , intensive care medicine , myocardial infarction , computer science , artificial intelligence , physical therapy , social science , computer security , sociology

After 2 decades of development and use in interventional cardiology research, optical coherence tomography (OCT) has now become a core intravascular imaging modality in clinical practice. Its unprecedented spatial resolution allows visualization of the key components of the atherosclerotic plaque that appear to confer "vulnerability" to rupture-namely the thickness of the fibrous cap, size of the necrotic core, and the presence of macrophages. The utility of OCT in the evaluation of plaque composition can provide insights into the pathophysiology of acute coronary syndrome and the healing that occurs thereafter. A brief summary of the principles of OCT technology and a comparison with other intravascular imaging modalities is presented. The review focuses on the current evidence for the use of OCT in identifying vulnerable plaques in acute coronary syndrome and its limitations.

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