Prognostic Value of Microvascular Obstruction and Infarct Size, as Measured by CMR in STEMI Patients | Zendy

Matthijs van Kranenburg | Zendy; Michael Magro | Zendy; Holger Thiele | Zendy; Suzanne de Waha | Zendy; Ingo Eitel | Zendy; Alexandre Cochet | Zendy; Yves Cottin | Zendy; Dan Atar | Zendy; Peter Buser | Zendy; Edwin Wu | Zendy; Daniel Lee | Zendy; Vicente Bodı́ | Zendy; Gert Klug | Zendy; Bernhard Metzler | Zendy; Ronak Delewi | Zendy; Peter Bernhardt | Zendy; Wolfgang Rottbauer | Zendy; Eric Boersma | Zendy; Felix Zijlstra | Zendy; RobertJan van Geuns | Zendy

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Prognostic Value of Microvascular Obstruction and Infarct Size, as Measured by CMR in STEMI Patients

Author(s) -

Matthijs van Kranenburg,

Michael Magro,

Holger Thiele,

Suzanne de Waha,

Ingo Eitel,

Alexandre Cochet,

Yves Cottin,

Dan Atar,

Peter Buser,

Edwin Wu,

Daniel Lee,

Vicente Bodı́,

Gert Klug,

Bernhard Metzler,

Ronak Delewi,

Peter Bernhardt,

Wolfgang Rottbauer,

Eric Boersma,

Felix Zijlstra,

RobertJan van Geuns

Publication year - 2014

Publication title -

jacc. cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.79

H-Index - 120

eISSN - 1936-878X

pISSN - 1876-7591

DOI - 10.1016/j.jcmg.2014.05.010

Subject(s) - mace , cardiology , hazard ratio , medicine , myocardial infarction , percutaneous coronary intervention , confidence interval , heart failure

The aim of this study was to evaluate the value of microvascular obstruction (MO) and infarct size as a percentage of left ventricular mass (IS%LV), as measured by contrast-enhanced cardiac magnetic resonance, in predicting major cardiovascular adverse events (MACE) at 2 years in patients with ST-segment elevation myocardial infarction reperfused by primary percutaneous coronary intervention. Individual data from 1,025 patients were entered into the pooled analysis. MO was associated with the occurrence of MACE, defined as a composite of cardiac death, congestive heart failure, and myocardial re-infarction (adjusted hazard ratio: 3.74; 95% confidence interval: 2.21 to 6.34). IS%LV ≥25% was not associated with MACE (adjusted hazard ratio: 0.90; 95% confidence interval: 0.59 to 1.37). The authors conclude that MO is an independent predictor of MACE and cardiac death, whereas IS%LV is not independently associated with MACE.

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