Collagen-Specific Peptide Conjugated HDL Nanoparticles as MRI Contrast Agent to Evaluate Compositional Changes in Atherosclerotic Plaque Regression | Zendy

Wei Chen | Zendy; David P. Cormode | Zendy; Yuliya Vengrenyuk | Zendy; Beatriz Herránz | Zendy; Jonathan E. Feig | Zendy; Ahmed Klink | Zendy; Willem J. M. Mulder | Zendy; Edward A. Fisher | Zendy; Zahi A. Fayad | Zendy

Open Access

Collagen-Specific Peptide Conjugated HDL Nanoparticles as MRI Contrast Agent to Evaluate Compositional Changes in Atherosclerotic Plaque Regression

Author(s) -

Wei Chen,

David P. Cormode,

Yuliya Vengrenyuk,

Beatriz Herránz,

Jonathan E. Feig,

Ahmed Klink,

Willem J. M. Mulder,

Edward A. Fisher,

Zahi A. Fayad

Publication year - 2013

Publication title -

jacc. cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.79

H-Index - 120

eISSN - 1936-878X

pISSN - 1876-7591

DOI - 10.1016/j.jcmg.2012.06.016

Subject(s) - in vivo , ex vivo , magnetic resonance imaging , chemistry , in vitro , gadolinium , macrophage , nanoparticle , pathology , biophysics , biochemistry , medicine , materials science , nanotechnology , biology , microbiology and biotechnology , organic chemistry , radiology

This study sought to develop magnetic resonance contrast agents based on high-density lipoprotein (HDL) nanoparticles to noninvasively visualize intraplaque macrophages and collagen content in mouse atherosclerotic plaques.

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