Effects of p38 Mitogen-Activated Protein Kinase Inhibition on Vascular and Systemic Inflammation in Patients With Atherosclerosis | Zendy

Maysoon Elkhawad | Zendy; James H.F. Rudd | Zendy; Lea SarovBlat | Zendy; Gengqian Cai | Zendy; R. J. Wells | Zendy; Ceri Davies | Zendy; David Collier | Zendy; Michael Marber | Zendy; Robin P. Choudhury | Zendy; Zahi A. Fayad | Zendy; Ahmed Tawakol | Zendy; Fergus Gleeson | Zendy; John J. Lepore | Zendy; Bill Davis | Zendy; Robert N. Willette | Zendy; Ian B. Wilkinson | Zendy; Dennis L. Sprecher | Zendy; Joseph Cheriyan | Zendy

Open Access

Effects of p38 Mitogen-Activated Protein Kinase Inhibition on Vascular and Systemic Inflammation in Patients With Atherosclerosis

Author(s) -

Maysoon Elkhawad,

James H.F. Rudd,

Lea SarovBlat,

Gengqian Cai,

R. J. Wells,

Ceri Davies,

David Collier,

Michael Marber,

Robin P. Choudhury,

Zahi A. Fayad,

Ahmed Tawakol,

Fergus Gleeson,

John J. Lepore,

Bill Davis,

Robert N. Willette,

Ian B. Wilkinson,

Dennis L. Sprecher,

Joseph Cheriyan

Publication year - 2012

Publication title -

jacc. cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.79

H-Index - 120

eISSN - 1936-878X

pISSN - 1876-7591

DOI - 10.1016/j.jcmg.2012.02.016

Subject(s) - medicine , placebo , inflammation , fluorodeoxyglucose , c reactive protein , positron emission tomography , clinical endpoint , confidence interval , p38 mitogen activated protein kinases , statin , gastroenterology , cardiology , protein kinase a , randomized controlled trial , kinase , pathology , nuclear medicine , alternative medicine , biology , microbiology and biotechnology

This study sought to determine the effects of a p38 mitogen-activated protein kinase inhibitor, losmapimod, on vascular inflammation, by (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography imaging.

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