4-[18F]-Tetraphenylphosphonium as a PET Tracer for Myocardial Mitochondrial Membrane Potential | Zendy

Gagandeep S. Gurm | Zendy; Stephan B. Danik | Zendy; Timothy M. Shoup | Zendy; Steven B. Weise | Zendy; Kazue Takahashi | Zendy; Shawna Laferrier | Zendy; David R. Elmaleh | Zendy; Henry Gewirtz | Zendy

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4-[18F]-Tetraphenylphosphonium as a PET Tracer for Myocardial Mitochondrial Membrane Potential

Author(s) -

Gagandeep S. Gurm,

Stephan B. Danik,

Timothy M. Shoup,

Steven B. Weise,

Kazue Takahashi,

Shawna Laferrier,

David R. Elmaleh,

Henry Gewirtz

Publication year - 2012

Publication title -

jacc. cardiovascular imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.79

H-Index - 120

eISSN - 1936-878X

pISSN - 1876-7591

DOI - 10.1016/j.jcmg.2011.11.017

Subject(s) - in vivo , blood flow , nuclear medicine , positron emission tomography , microsphere , chemistry , ex vivo , medicine , adenosine , tracer , cardiology , in vitro , biochemistry , physics , microbiology and biotechnology , chemical engineering , nuclear physics , engineering , biology

This study tested the hypothesis that 4-[(18)F]fluorophenyltriphenylphosphonium ((18)F-TPP) is useful for in vivo positron emission tomography (PET) measurement of mitochondrial membrane potential (ΔΨm). Its utility as a blood flow tracer also was evaluated.

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