Ultrasound-Targeted Gene Delivery Induces Angiogenesis After a Myocardial Infarction in Mice
Author(s) -
Hiroko Fujii,
Zhuo Sun,
Shu-Hong Li,
Jun Wu,
Shafie Fazel,
Richard D. Weisel,
Harry Rakowski,
Jonathan R. Lindner,
RenKe Li
Publication year - 2009
Publication title -
jacc. cardiovascular imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.79
H-Index - 120
eISSN - 1936-878X
pISSN - 1876-7591
DOI - 10.1016/j.jcmg.2009.04.008
Subject(s) - gene delivery , microbubbles , medicine , perfusion , angiogenesis , vascular endothelial growth factor , myocardial infarction , progenitor cell , genetic enhancement , ligation , cardiology , pathology , stem cell , biology , gene , ultrasound , microbiology and biotechnology , vegf receptors , biochemistry , radiology
This study evaluated the capacity of ultrasound-targeted microbubble destruction (UTMD) to deliver angiogenic genes, improve perfusion, and recruit progenitor cells after a myocardial infarction (MI) in mice.
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