Electroacupuncture Promotes Neural Proliferation in Hippocampus of Perimenopausal Depression Rats via Wnt/β-Catenin Signaling Pathway
Author(s) -
Jing Qin,
Lu Ren,
Xue Deng,
Nan Zhang,
Martin M. Fu,
Ge Wang,
Xi-Rong Jiang,
Lin Shu-ru,
Cai-Rong Ming
Publication year - 2020
Publication title -
journal of acupuncture and meridian studies
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.374
H-Index - 32
eISSN - 2093-8152
pISSN - 2005-2901
DOI - 10.1016/j.jams.2020.03.065
Subject(s) - electroacupuncture , hippocampus , wnt signaling pathway , depression (economics) , catenin , medicine , neuroscience , signal transduction , acupuncture , biology , microbiology and biotechnology , alternative medicine , pathology , macroeconomics , economics
Perimenopausal depression is caused by the impaired function of the ovarium before menopause and with a series of symptoms. Electroacupuncture (EA) therapy has been demonstrated to improve clinically depression. However, the mechanism underlying its therapeutic activity remains unknown. This study aimed to investigat the effects of EA treatment on the hippocampal neural proliferation through Wnt signaling pathway.
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