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Sleep and neurocognitive decline in the Hispanic Community Health Study/Study of Latinos
Author(s) -
Ramos Alberto R.,
Tarraf Wassim,
Wu Benson,
Redline Susan,
Cai Jianwen,
Daviglus Martha L.,
Gallo Linda,
MossavarRahmani Yasmin,
Perreira Krista M.,
Zee Phyllis,
Zeng Donglin,
Gonzalez Hector M.
Publication year - 2020
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.08.191
Subject(s) - neurocognitive , cognitive decline , insomnia , psychology , sleep (system call) , population , medicine , audiology , episodic memory , cognition , demography , gerontology , psychiatry , dementia , disease , environmental health , sociology , computer science , operating system
To determine if sleep‐disordered breathing (SDB), daytime sleepiness, insomnia, and sleep duration predict seven‐year neurocognitive decline in US Hispanics/Latinos (N = 5247). Methods The exposures were baseline SDB, daytime sleepiness, insomnia, and sleep duration. The outcomes were change in episodic learning and memory (B‐SEVLT‐Sum and SEVLT‐Recall), language (word fluency [WF]), processing speed (Digit Symbol Substitution), and a cognitive impairment screener (Six‐item Screener [SIS]). Results Mean age was 63 ± 8 years, with 55% of the population being female with 7.0% Central American, 24.5% Cuban, 9.3% Dominican, 35.9% Mexican, 14.4% Puerto Rican, and 5.1% South American background. Long sleep (>9 hours), but not short sleep (<6 hours), was associated with decline (standard deviation units) in episodic learning and memory (β SEVLT‐Sum = −0.22 [se = 0.06]; P < .001; β SEVLT‐Recall = −0.13 [se = 0.06]; P < .05), WF (Pwf = −0.20 [se 5 0.06]; P < .01), and SIS (β SIS = −0.16 [se = 0.06]; P < .01), but not processing speed, after adjusting for covariates. SDB, sleepiness, and insomnia were not associated with neurocognitive decline. Conclusion Long sleep duration predicted seven‐year cognitive decline.