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P4‐554: AN EHR‐BASED COHORT DISCOVERY TOOL FOR IDENTIFYING PROBABLE AD
Author(s) -
Tjandra Donna,
Migrino Raymond,
Giordani Bruno,
Wiens Jenna
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.08.101
Subject(s) - medical diagnosis , cohort , medicine , medical record , ranking (information retrieval) , confidence interval , computer science , diagnosis code , disease , artificial intelligence , data mining , pathology , population , environmental health
neuropsychological test scores in older surgical patients presenting for elective spine operations. Methods: This was a prospective cohort study of 52 patients aged 65-89 years, having elective, inpatient spine surgery under general anesthesia. To determine the validity of cognitive screening using the Mini-Cog, we compared Mini-Cog scores with neuropsychological test scores. Neuropsychological tests included Digit Symbol Substitution to test attention and concentration, Animal Category Fluency and Trail Making Tests A & B to test executive function, and CERADWord List Delayed Recall, Logical Memory Immediate & Delayed Recall to test Memory. Clinical Dementia Rating (CDR) and Instrumental Activities of Daily Living (IADL) were also assessed. Results: Of 52 patients enrolled, 9 patients scored between 0-2 (compatible with cognitive impairment) on the Mini-Cog, while 43 scored between 3-5. There were significant differences between the two groups in Digit Symbol Substitution Test scores (p1⁄40.02), CERAD Word List Delayed Recall (p1⁄40.05), Trail Making Test A (p<0.001), and Trail Making Test B (p<0.01). (See table) Of note, there was no difference between the two groups Mini-Mental State Examination scores. The two groups also had significantly different Clinical Dementia Ratings (p1⁄40.02) and Instrumental Activities of Daily Living scores (p<0.01). Conclusions: These data support the validity of administering the Mini-Cog as a brief screening tool for cognitive impairment in older patients presenting for elective spine surgery. P4-554 AN EHR-BASED COHORT DISCOVERY TOOL FOR IDENTIFYING PROBABLE AD Donna Tjandra, Raymond Migrino, Bruno Giordani, Jenna Wiens, University of Michigan, Ann Arbor, MI, USA; Phoenix Veterans Affairs Health Care System, Phoenix, AZ, USA. Contact e-mail: dotjandr@umich.edu