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P1‐261: DEVELOPMENT OF A UNIFIED ‐OMIC PREPARATION METHODOLOGY: AN ALTERNATIVE, NON‐IP APPROACH TO TARGETED LC‐MS/MS DETECTION OF SECRETED AMYLOID‐β PEPTIDES IN CEREBROSPINAL FLUID AND IPSC‐DERIVED FAMILIAL ALZHEIMER'S DISEASE MODELS
Author(s) -
Leckey Claire Alexandra,
Hällqvist Jenny,
Doykov Ivan Dimitrov,
Mills Kevin,
Wray Selina,
Fox Nick C.,
Zetterberg Henrik,
Paterson Ross W.
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.816
Subject(s) - cerebrospinal fluid , chromatography , chemistry , elution , peptide , mass spectrometry , sample preparation , triple quadrupole mass spectrometer , solid phase extraction , computational biology , biochemistry , tandem mass spectrometry , biology , selected reaction monitoring , neuroscience