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O5‐03‐01: AFFORDABLE EEG MARKERS FOR THE SCREENING OF COGNITIVE IMPAIRMENT OF OLD ADULTS
Author(s) -
Kim Jaeuk U.,
Choi Jungmi,
Ku Boncho Uk,
Kim Gahye,
Kim Joong Il,
Kim Soochan,
Cha Wonseok
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.4846
Subject(s) - electroencephalography , dementia , audiology , cognitive impairment , resting state fmri , cognition , cognitive decline , medicine , psychology , psychiatry , neuroscience , disease
avidity and scavenging, cytokine associations. Results: Receptor CCRL2-V180M has a higher binding assay with Chemerin than wildtype (p-value 0.03; 15 samples). There is a chemical change at the SNP site. CCL4 does not interfere with interaction between CCRL2 and Chemerin. Results for avidity and scavenging assays as well as an association analysis will be reported at the conference. Conclusions: This work will provide insights into the association of CCRL2-V180M with AD risk, rate of cognitive decline, and serum markers of inflammation which could lead to novel therapeutic solutions for AD.