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F1‐04‐04: THE SCD‐WELL RANDOMIZED CONTROLLED TRIAL: EFFECTS OF A MINDFULNESS‐BASED INTERVENTION VERSUS HEALTH EDUCATION ON MENTAL HEALTH AND COGNITION IN PATIENTS WITH SUBJECTIVE COGNITIVE DECLINE
Author(s) -
Marchant Natalie L.,
Barnhofer Thorsten,
Wirth Miranka,
Coueron Roxane,
Lutz Antoine,
Collette Fabienne,
Poisnel Géraldine,
Schild Ann-Katrin,
Coll-Padros Nina,
Demnitz-King Harriet,
Reyrolle Leslie,
Whitfield Tim,
Frison Eric,
Asselineau Julien,
Walker Zuzana,
Salmon Pierre Krolak,
Molinuevo Jose Luis,
Chetelat Gaelle,
Jessen Frank,
Klimecki Olga
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.4384
Subject(s) - medicine , mindfulness , randomized controlled trial , dementia , anxiety , cognitive decline , cognition , physical therapy , psychiatry , clinical psychology , disease
Subjectively experienced cognitive decline in older adults is an indicator of increased risk for dementia and is also associated with increased levels of anxiety symptoms. As anxiety is itself emerging as a risk factor for cognitive decline and dementia, the primary question of the present study is whether an 8-week mindfulness-based intervention can significantly reduce anxiety symptoms in patients with subjective cognitive decline (SCD). The secondary questions pertain to whether such changes extend to other domains of psychological, social, and biological functioning (including cognition, self-regulation, lifestyle, well-being and quality of life, sleep, and selected blood-based biomarkers) associated with mental health, older age, and risk for dementia.