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IC‐P‐150: [C‐11]MK‐6884 PET: CHARACTERIZING BRAIN M4 RECEPTORS IN HEALTHY ELDERLY VOLUNTEERS AND ACETYLCHOLINESTERASE INHIBITORS‐TREATED AD PATIENTS
Author(s) -
Wang Yuchuan,
Li Wenping,
Lohith Talakad G.,
Bormans Guy,
Koole Michel,
Van Laere Koen,
Serdons Kim,
Hoon Jan,
Declercq Ruben,
De Lepeleire Inge,
Pascual Maria B.,
Zanotti-Fregonara Paolo,
Yu Meixiang,
Arbones Victoria,
Masdeu Joseph C.,
Cheng Amy,
Anderson Matt S.,
Hostetler Eric D.,
Basile Anthony S.
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.4264
Subject(s) - donepezil , rivastigmine , medicine , acetylcholinesterase , binding potential , striatum , cholinergic , nuclear medicine , dementia , pharmacology , neuroscience , receptor , endocrinology , psychology , dopamine , disease , chemistry , biochemistry , enzyme
IC-P-150 [C-11]MK-6884 PET: CHARACTERIZING BRAIN M4 RECEPTORS IN HEALTHY ELDERLY VOLUNTEERS AND ACETYLCHOLINESTERASE INHIBITORSTREATED AD PATIENTS Yuchuan Wang, Wenping Li, Talakad G. Lohith, Guy Bormans, Michel Koole, Koen Van Laere, Kim Serdons, Jan de Hoon, Ruben Declercq, Inge De Lepeleire, Maria B. Pascual, Paolo ZanottiFregonara, Meixiang Yu, Victoria Arbones, Joseph C. Masdeu, Amy Cheng, Matt S. Anderson, Eric D. Hostetler, Anthony S. Basile, Merck & Co., Inc., Kenilworth, NJ, USA; Radiopharmaceutical Research, Department of Pharmacology, KU Leuven, Leuven, Belgium; KU Leuven and University Hospital Leuven, Leuven, Belgium; Nuclear Medicine, KU Leuven and University Hospital Leuven, Leuven, Belgium; Merck Sharp & Dohme (Europe) Inc., Brussels, Belgium; Houston Methodist Neurological Institute, Houston, TX, USA. Contact e-mail: yuchuan.wang@merck.com