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P4‐451: FISH AND MEAT CONSUMPTION ASSOCIATED WITH BRAIN STRUCTURAL MEASUREMENT IN OLDER ADULTS
Author(s) -
GU Yian,
Manly Jennifer J.,
Scarmeas Nikolaos,
Schupf Nicole,
Mayeux Richard,
Brickman Adam M.
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.4123
Subject(s) - cohort , population , brain size , mediterranean diet , medicine , fish <actinopterygii> , zoology , demography , biology , environmental health , fishery , magnetic resonance imaging , sociology , radiology
family history interaction indicated that FH+ had worse declines in fluid intelligence for white wine intake (FH-: b1⁄4-.047, p<.05; FH+: b1⁄4-.101, p<.05). Conclusions: Results suggest that greater weekly cheese and grain intake over 6 years was associated with better fluid intelligence performance, while greater vegetable and white wine intake were detrimental. APOE4 and AD FH could modify the effect of some dietary factors on fluid intelligence. Thus, dietary meal plans may need to be personalized for participants to potentially minimize cognitive decline.