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P4‐371: CHANGES IN SEMANTIC STRUCTURE AND FREE RECALL DUE TO COGNITIVE IMPAIRMENT AND NORMAL COGNITIVE AGING
Author(s) -
Westfall Holly A.,
Bock Jason R.,
Mangrola Tushar,
Lee Michael D.
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.4042
Subject(s) - free recall , recall , semantic similarity , semantic memory , cognition , recall test , similarity (geometry) , statistic , psychology , representation (politics) , cognitive psychology , artificial intelligence , computer science , mathematics , statistics , neuroscience , politics , political science , law , image (mathematics)
are lacking. The aim of this study is to establish reliable change indices (RCI) for MoCA-P among healthy Filipino older adults. Methods: A total of 315 community dwelling Filipino older adults aged 60-86 years old met inclusion for the study. Participants were identified cognitively normal both at baseline and follow-up based on multidisciplinary consensus. The MoCA-P was administered twice with a 5-year follow-up interval. The RCI methods by Chelune and Hsu were used. Results: In a repeated assessment, a change in MoCA-P scores (-5 , 7 points) indicated a reliable change at the 90% confidence interval. It was also found that the RCI (Chelune), was significantly different among the groups and as well as the pairwise comparisons of pretest MoCA-P score levels. Test-retest reliability was considerably strong and significant. (r1⁄40.694; p < 0.05). A higher RCI for MoCA-P were found in this study as compared to other population-based change norms. This is explained by longer year of follow-up period. Conclusions: The study provided RCI for MoCA-P that can be used for the estimation of cognitive decline or improvement in clinical settings with longer year follow-up interval. Small changes in MoCA-P scores should be interpreted with caution as the probability of change can also be reasonably due to measurement error, regression to mean, practice, as well as normal aging with consideration to the length of follow-up interval.