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P4‐149: P2RX7 INHIBITOR SUPPRESSES EXOSOME SECRETION, DELAYS PROTEOPATHIC TAU ACCUMULATION AND MEMORY IMPAIRMENT IN PS19 P301S TAU MICE
Author(s) -
Ruan Zhi,
Delpech Jean Christophe,
Mina Botros,
Van Enoo Alicia,
Wang Katherine,
Ikezu Seiko,
Ikezu Tsuneya
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.3810
Subject(s) - hippocampal formation , exosome , stimulation , secretion , microvesicles , hippocampus , microglia , tau protein , extracellular , medicine , endocrinology , chemistry , microbiology and biotechnology , alzheimer's disease , pharmacology , biology , biochemistry , microrna , inflammation , disease , gene