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P3‐179: ABERRANT PERK ACTIVATION IS ASSOCIATED WITH THE DEPLETION OF NRF2 SIGNALING AND THE INCREASE OF OXIDATIVE BURDEN IN DS PATHOLOGY
Author(s) -
Perluigi Marzia,
Lanzillotta Chiara,
Zuliani Ilaria,
Barone Eugenio,
Abisambra Joe F.,
Di Domenico Fabio
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.3208
Subject(s) - unfolded protein response , endoplasmic reticulum , oxidative stress , western blot , microbiology and biotechnology , biology , neuroscience , cancer research , medicine , endocrinology , gene , biochemistry