Premium
P2‐590: EFFECT OF FIVE WEEKS OF DIFFERENT STRUCTURED INTERVENTIONS ON SERUM BDNF LEVELS IN HEALTHY OLDER ADULTS
Author(s) -
Ledreux Aurélie,
Håkansson Krister,
Carlsson Roger,
Columbo Laura,
Kidane Mhretab,
Feng Nicole C.,
Tusch Erich S.,
Terjestam Yvonne,
Ryan Eliza,
Mohammed Abdul H.,
Granholm Ann-Charlotte,
Daffner Kirk R.
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.2999
Subject(s) - cognitive training , cognition , neuroplasticity , brain derived neurotrophic factor , medicine , psychological intervention , population , psychology , mindfulness , neurotrophic factors , clinical psychology , physical therapy , psychiatry , receptor , environmental health
physical activity. We analyzed the relationship between global cognition (Mini Mental Status Examination (MMSE)) and self-reported walking, jogging and aerobic exercise on Modified National Health Interview Survey, ExercisePhysical Activity Questionnaire. Metabolic equivalents (METS) were calculated for walking, jogging/running, and aerobic exercise. Results: Participants were predominantly females (99%) and averaged 67 years in age. A linear regression analysis, using MMSE scores as dependent variable and tested whether walking, jogging/ running or doing aerobic exercise associated with memory. Unadjusted results showed significant difference only in the aerobic group, but not significant after adjusted for age, sex, and gender. When we modeled walking, jogging/running or doing aerobic exercise METS as predictor variables, aerobic exercise was significantly associated with MMSE in the initial unadjusted regression analyzes. This relationship remained significant after discounting the effects of age, sex, and gender. Conclusions: Although self-reported aerobic exercise is associated with better performance on the MMSE test, less than 1% of our AA sample reported performing aerobic exercise, while 30% self-reported walking. We conclude that physical activity is beneficial to performance on cognitive tasks. Larger prospective study is needed to validate our findings in AAs.