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P2‐534: POSITIVE AFFECT AS A PREDICTOR OF INCIDENT MILD COGNITIVE IMPAIRMENT AND DEMENTIA
Author(s) -
Umucu Emre,
Wyman Mary F.,
Lee Beatrice,
Mangadu Thenral,
Benton Susan Flowers,
Zuelsdorff Megan,
Lambrou Nickolas,
Skenandore Donald W.,
Bogues Shenikqua,
Johnson Sterling C.,
Carlsson Cynthia,
Asthana Sanjay,
Gleason Carey E.
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.2942
Subject(s) - affect (linguistics) , dementia , hazard ratio , medicine , geriatric depression scale , cognition , depression (economics) , psychology , disease , gerontology , clinical psychology , psychiatry , confidence interval , depressive symptoms , communication , macroeconomics , economics
adjusted OR 1⁄4 2.69, 95% confidence interval (CI) 1⁄4 1.11–6.55). After stratification by gender, this association attenuated in men (OR 1⁄4 1.22, 95% CI 1⁄4 0.22-6.67). In addition, the associations were borderline significant for the four cognition domains. Conclusions: This study found that sarcopenia was associated with an increased risk of global cognitive impairment in the communitydwelling old adults. Future longitudinal studies are warranted to confirm their causal-relationship.