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P2‐400: MICROGLIAL ACTIVATION DETECTED BY NOVEL TSPO TRACER FLUTRICICLAMIDE ([11FGE180]) IN AD AND MCI SUBJECTS
Author(s) -
Calsolaro Valeria,
Femminella Grazia Daniela,
Buckley Christopher,
Turkheimer Federico,
Gentleman Steve,
Hinz Rainer,
Brooks David J.,
Edison Paul
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.2807
Subject(s) - translocator protein , medicine , neuroinflammation , nuclear medicine , temporal lobe , cognitive impairment , pathology , alzheimer's disease , cardiology , psychology , neuroscience , disease , epilepsy
being increased and more diverse populations are being included. Finally, clinical applications of these brain maps are explored. Conclusions: The UNITED consortium is a novel collaboration that aims to realize an in-depth depiction of the diseased brain. Preliminary results indicate that high-resolution analyses of the brain hold great value for understanding neurodegenerative diseases, and have the potential for translation into the clinic.