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P2‐313: DYSEXECUTIVE SYNDROME IN MULTI‐INFARCT VERSUS SUBCORTICAL ISCHAEMIC SMALL VESSEL DISEASE DEMENTIA
Author(s) -
Semnic Marija D.,
Semnic Robert R.,
Kozic Dusko B.
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.2720
Subject(s) - wisconsin card sorting test , dementia , dysexecutive syndrome , cognitive flexibility , neuropsychology , stroke (engine) , psychology , vascular dementia , audiology , medicine , psychiatry , cognition , disease , mechanical engineering , engineering
dementia and 60 years of age or more from the Optum Insight Clinformatics-data Mart database was followed from 2005 to 2014. Group differences were analyzed using continuity-adjusted chisquare and hazard ratios with 95% confidence intervals calculated after a logistic regression analysis.Results: A total ofN1⁄479,561 patients (2.8%) from the cohort had a dementia diagnosis, with 56% of them been women. Dementia patients were found to have 6.5 times increased risk for undifferentiated seizures, a 6 fold elevated risk for partial seizures, and 5.2 times higher risk for generalized and undifferentiated epilepsy. Also, patients with a dementia diagnosis had 4.75 increased risk for generalized seizures, and partial epilepsy. Conclusions: In conclusion, based on U.S. national managed care database, patients of 60 years of age or older have higher risks of new onset seizures associated with a dementia diagnosis. The risk of new onset seizures associated with a diagnosis of dementia suggests the need for clinicians to monitor for seizures to ensure that patients with dementia receive an appropriate treatment