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P2‐304: AN ECONOMIC EVALUATION OF A NOVEL COMPUTERIZED COGNITIVE TEST IN DEMENTIA
Author(s) -
Schneider John E.,
Cooper Jacie
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.2711
Subject(s) - dementia , medicine , offset (computer science) , cognition , disease , cohort , perspective (graphical) , computer science , risk analysis (engineering) , operations management , intensive care medicine , actuarial science , engineering , business , artificial intelligence , psychiatry , pathology , programming language
Background: Frontotemporal dementia (FTD) is a neurodegenerative disorders associated with degeneration of the frontal and temporal lobes. The patients may present with a wide range of symptoms, including prominent neuropsychiatric symptoms that often mimic other psychiatric disorders. Initial psychiatric diagnoses, such as psychosis or depression, are common. Early diagnosis of FTD may challenge due to behavioral and psychotic symptoms. Methods: A patient with FTD misdiagnosed as psychosis was presented as case report in this paper. Results: A female patient, 57 years, female, had depressive symptoms, include personality and behavioral changes for 3 years. She was admitted to a psychiatry clinic with newly developed psychotic symptoms, consisting of both delusions and auditory hallucinations. Thus, she was diagnosed as psychosis and treated antipsychotic drugs (amisulpride and quetiapin). However, the patient’s complains was progressed in time and there was no reponse to treatment. Then she developed progressive apathy, compulsiveness, and executive dysfunction. The patient history include that the patient’s mother and two aunts had similar symptoms at similar ages but they were not diagnosed. After last visit of psychiatry clinic the patient was referred to neurology dementia clinic. The patient’s MMSE score was 21/30. Also, she had high depression score. Scores of frontal lobe battery test was impaired and it was found associated with FTD. There was seen markedly frontal and parietal atrophy on cranial MRI scan. Conclusions: Currently, psychotic symptoms are not included in current diagnostic criteria for FTD, but need to be considered in differential diagnosis of patients with FTD. Also, the risk of misdiagnosis is particularly high in these individuals being diagnosed with psychiatric rather than neurodegenerative disease.