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P2‐296: DECISION MAKING TIME IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT AND DEMENTIA ASSESSED WITH SIMPLE REACTION TIME AND GO/NO‐GO TASK
Author(s) -
Bragin Valentin,
Lashiker Nicole,
Kalancha David,
Silenko Tanya,
Nozadze Sally
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.2703
Subject(s) - neurocognitive , dementia , verbal fluency test , cohort , audiology , cognition , cognitive impairment , memory clinic , neuropsychology , psychology , medicine , psychiatry , disease
fasting glucose levels were associated with lower IICV, but a diagnosis of diabetes was associated with increased IICV (See Table 2). Conclusions: From previous studies, we know that greater IICV is associated with an increased risk of incident dementia or mild cognitive impairment (MCI). For cognitively healthy individuals in our study, education and white race had reduced IICV scores. 9% of variance in IICV could be explained by demographic covariates (education and white race). Lipid values did not statistically explain any variance in IICV for healthy individuals. Co-morbidities including fasting glucose, WHR, and non-diabetic status were negatively associated with IICV. For the cognitively impaired individuals, increased age and reduced education were significantly associated with increased IICV scores. Contrary to expectations, lipid pathology was not associated with IICV but markers of metabolic health and demographic factors were associated with cognitive variability.