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P2‐268: VALIDITY OF THE EVERYDAY COGNITION (ECOG) AS A SCREENING MEASURE OF SUBJECTIVE COGNITIVE DECLINE (SCD)
Author(s) -
Song Minji,
Hwa Lee Sun,
Kang Yeonwook
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.2675
Subject(s) - cognition , dementia , geriatric depression scale , psychology , depression (economics) , cognitive decline , mini–mental state examination , clinical psychology , cognitive impairment , audiology , gerontology , medicine , psychiatry , disease , depressive symptoms , economics , macroeconomics
questionnaire and a complete dementia survey including blood tests, neuropsychological tests, cerebral MRI, and nuclear imagines including Tc99m-TRODAT and Tc99m ECD SPECT. Subtypes of dementia and were compared between the history-based diagnosis and the final diagnosis by a consensus meeting composed of neurologists, geriatric psychiatrists, neuropsychologists, neuroradiologists, and nuclear medicine doctors. Results: The final diagnosis (FD) of all participants were 25 non-demented (ND), 27 Alzheimer’s disease (AD), 29 vascular dementia (VaD), 130 dementia with Lewy bodies/Parkinson’s disease dementia (DLB/PDD), and 23 other dementia (OD). Comparison between the history-based diagnosis (HD) and the FD of all participants showed good compatibilities in subtypes (76.7%) and severity (82.1%). The compatibilities of each subtypes of dementia is highest in ND (92.0%), followed by AD (85.7%), DLB/PDD (82.1%), VaD (68.6%), and OD (50%). Conclusions: Our study demonstrated a high compatibility of diagnosis based only on the clinical history with the final diagnosis. According to most criteria for different types of dementia, a detailed clinical history is essential and always the first step to make a diagnosis of dementia. Further machine learning of the structured and standardized questionnaire to achieve more accurate diagnosis of dementia should be warranted.

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