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P2‐224: DECREASED LEVELS OF CSF ABETA40 IN DEMENTIA WITH LEWY BODIES
Author(s) -
Kanemaru Kazutomi,
Kanemaru Akiko,
Murayama Shigeo
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.2631
Subject(s) - dementia with lewy bodies , medicine , neurology , cerebrospinal fluid , dementia , gastroenterology , alzheimer's disease , pathology , disease , psychiatry
based training on mannequins with an evaluation of the training by the students; 3/ After optimization, deployment of this training to fourth year medical students; 4/ Evaluation by a prospective randomized study on two groups of students (with or without prior training) to assess the impact of this training on the success rate of their first LP on a patient. Results: Before training, the average score at MRQs was 4.4 out of 10 (SD 1.4). The training allowed an improvement of the level of theoretical knowledge and confidence in the performance of LP (p<0.0001). The randomized study of 41 students showed a trend towards a better success rate of the first LP on a patient for the group with versus without prior training (74% vs 57%, p1⁄40.307). Moreover, technical assistance was less frequent in the group with prior training (19% vs 57%, p1⁄40.017). Conclusions: Students’ theoretical and practical knowledge was noticeably improved by the training. Although the lack of power of the randomized study does not allow to conclude with certainty, LP simulation-based training seems to bring a real benefit with a decrease in technical assistance and a better experience for students regarding their first LP on a patient. A long delay between the training and the performance of LP on a patient could limit this benefit. P2-223 STABILITY OF PLASMA AMYLOID-b 1-40, AMYLOID-b 1-42 AND TOTALTAU OVER REPEATED FREEZE/THAW CYCLES H. C. Liu, Ming-Jang Chiu, Chin-Hsien Lin, Wen-Ping Chen, Shieh-Yueh Yang, MagQu Co., Ltd., New Taipei City, Taiwan; National Taiwan University Hospital, Taipei, Taiwan; MagQu LLC, Surprise, AZ, USA; MagQu Co., Ltd., Taiwan, New Taipei City, Taiwan. Contact e-mail: syyang@magqu.com