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P2‐208: LACK OF TREM2 AFFECTS THE PHENOTYPE AND TRANSCRIPTOME IN MICE EXPRESSING HUMAN APOE3 AND APOE4
Author(s) -
Fitz Nicholas F.,
Playso Brittany E.,
Wolfe Cody M.,
Nam Kyong Nyon,
Lefterov Iliya,
Koldamova Radosveta
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.2615
Subject(s) - trem2 , microglia , apolipoprotein e , neuroinflammation , biology , phenotype , neuroscience , immunology , medicine , disease , pathology , inflammation , genetics , gene
Gareth Howell, Daniela Kaufer, Garth F. Hall, Kun Ping Lu, Richard Ransohoff, Robin O. Cleveland, Neil W. Kowall, Bertrand R. Huber, Thor D. Stein, Bruce T. Lamb, William C. Moss, Alon Friedman, Patric K. Stanton, Ann C. McKee, Boston University School of Medicine, Boston, MA, USA; Boston University, Boston, MA, USA; New York Medical College, Valhalla, NY, USA; Cleveland Clinic, Cleveland, OH, USA; University of Massachusetts Lowell, Lowell, MA, USA; Harvard Medical School, Boston, MA, USA; BIDMC, Boston, MA, USA; The Jackson Laboratory, Bar Harbor, ME, USA; Ben-Gurion University, Beersheba, Israel; University of California, Berkeley, Berkeley, CA, USA; VA Boston Healthcare System, Jamaica Plain, MA, USA; Boston University School of Public Health, Boston, MA, USA; Lawrence Livermore National Laboratory, Livermore, CA, USA; BIDMC-Harvard Medical School, Boston, MA, USA; Biogen, Cambridge, MA, USA; University of Oxford, Oxford, United Kingdom; Boston University Alzheimer’s Disease Center, Boston, MA, USA; Indiana University, Stark Neurosciences Research Institute, Indianapolis, IN, USA. Contact e-mail: lgold@bu.edu