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P2‐133: INITIAL CHARACTERIZATION OF NOVEL MOUSE MODELS OF LATE ONSET ALZHEIMER'S DISEASE BASED ON HUMAN GENETIC ASSOCIATIONS
Author(s) -
Sasner Michael,
Oblak Adrian L.,
Preuss Christoph,
Garceau Dylan,
Williams Harriett,
Kotredes Kevin P.,
Ingraham Cynthia,
Pandey Ravi S.,
Uyar Asli,
Soni Disha,
Logsdon Benjamin A.,
Lamb Bruce T.,
Carter Gregory W.,
Howell Gareth
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.2540
Subject(s) - trem2 , transcriptome , biology , computational biology , humanized mouse , apolipoprotein e , in silico , human disease , genome wide association study , phenotype , disease , gene knockout , model organism , genetics , gene , medicine , immune system , gene expression , myeloid cells , genotype , single nucleotide polymorphism