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P1‐567: COGNITIVE IMPAIRMENT AND COMMUNITY RESOURCE NEEDS FOR OLDER MEXICAN AMERICANS: THE BRAIN ATTACK SURVEILLANCE IN CORPUS CHRISTI (BASIC)‐COGNITIVE PROJECT
Author(s) -
Briceno Emily M.,
Mehdipanah Roshanak,
Gonzales Xavier,
Heeringa Steven G.,
Levine Deborah A.,
Langa Kenneth M.,
Garcia Nelda,
Longoria Ruth,
Morgenstern Lewis
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.1172
Subject(s) - dementia , gerontology , population , cognition , ethnic group , cognitive decline , montreal cognitive assessment , neuropsychology , neuropsychological assessment , psychology , medicine , cognitive impairment , environmental health , disease , psychiatry , sociology , pathology , anthropology
them. CERAD was the only test used in 1999, when 15.2% were pre-menopausal and therefore was the only test used in this analysis. Mixed effect regression model was created to evaluate longitudinal relationship between time since FMP and cognition. Results: 252 WHAP participants with complete data were included in this analysis. Median (Q1-Q3) baseline time since FMP was 3.2(15.5) years. Time since FMP was negatively associated with CERAD delayed recall (b1⁄4-0.14, 95%CI -0.16 to -0.12, p<0.001) while controlling for education, APOE4, age at FMP and hormonal treatment at the time of cognitive testing. Conclusions:The results show that independent of potential confounders, prolonged time since FMP leads to decrease in cognitive function over 15 years. Further work needs to explore complex overlap between ageing, FMP and cognitive disease.