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P1‐540: MULTIDIMENSIONAL ITEM RESPONSE THEORY (IRT) FOR SURVEY HARMONIZATION AND DEMENTIA PREVALENCE PREDICTION IN THE GLOBAL BURDEN OF DISEASE (GBD) STUDY: AN EXAMPLE USING THE HEALTH AND RETIREMENT SURVEY (HRS)
Author(s) -
Nichols Emma,
Wang Chun,
Vos Theo
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.06.1145
Subject(s) - dementia , logistic regression , health and retirement study , medicine , gerontology , item response theory , population , demography , disease , psychometrics , clinical psychology , environmental health , sociology
Mental Status Exam (MMSE), Montreal Cognitive Assessment (MoCA), or the Digit Symbol Substitution Task (DSST) and the Short Physical Performance Battery (SPPB). The SPPB is comprised of a 4-meter walk, timed chair rise five times, and a balance test. Multiple linear regression models were applied across the whole sample (n1⁄4 929) and for each study. Results: Across all groups, there was a significant association between higher scores on the MMSE and better physical function (faster gait speed b1⁄4 0.02 meters/second(m/s) per point, p <0.001, chair rise time b1⁄4 -0.31 seconds per point, p 1⁄40.002, balance b1⁄4 0.06 per point, p <0.001, and SPPB b1⁄4 0.18 per point, p <0.001). Higher scores on the DSST produced similar and consistently significant results across all studies (faster gait speed b1⁄4 0.01 m/s per point, p <0.001, chair rise time b1⁄4 -0.08 seconds per point, p <0.001, balance b1⁄4 0.01 per point, p <0.001 and SPPB b1⁄4 0.06 per point, p <0.001). Conclusions: ADRC participants and older adults with various health conditions showed a consistent pattern between better cognitive function and better physical function. More research is needed to understand the complex interplay between cognition and physical function among older adults.

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