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Erratum to “Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies” [Alzheimer's & Dementia 2018;14:707‐22.]
Author(s) -
S.J. van der Lee,
Charlotte E. Teunissen,
Rene Pool,
Martin J. Shipley,
Alexander Teumer,
Vincent Chouraki,
D.M. van Lent,
Juho T Tynkkynen,
Krista Fischer,
Jussi Hernesniemi,
T. Haller,
Archana Singh-Manoux,
Aswin Verhoeven,
G. Willemsen,
F. A. de Leeuw,
Holger Wagner,
J. van Dongen,
Johannes Hertel,
Kathrin Budde,
Willems K. van Dijk,
Leonie Weinhold,
Ikram,
Maik Pietzner,
Markus Perola,
Michael von Wagner,
N Friedrich,
P. E. Slagboom,
P. Scheltens,
Qiong Yang,
Robert E. Gertzen,
Sarah Egert,
Siyao Li,
Thomas Hankemeier,
C.E.M. van Beijsterveldt,
Ramachandran S. Vasan,
Wolfgang Maier,
Carel F. W. Peeters,
Hans J. Grabe,
Alfredo Ramirez,
Sudha Seshadri,
A. Metspalu,
Mika Kivimäki,
Veikko Salomaa,
Ayse Demirkan,
Dorret I Boomsma,
M VanWinckel,
Najaf Amin,
C.M. van Duijn
Publication year - 2019
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2019.01.002
Subject(s) - dementia , cohort , medicine , cognition , gerontology , neuroscience , psychology , psychiatry , disease
In the article “Blood-brain barrier breakdown, neuroinflammation, and cognitive decline in older adults,” published in the December 2018 issue of Alzheimer’s & Dementia, the last sentence within the results and discussion of the abstract should be omitted to read as follows: “Mean age was 70 years, mean Mini–Mental State Examination was 27, and BBB impairment was recorded in 13.5%. BBB breakdown was associated with cognitive decline (P 5 .015). Cerebrospinal fluid intercellular adhesion molecule-1, vascular endothelial growth factor, interleukin-8, serum amyloid A, macrophage derived chemokine, and gender generated an area under the curve of 0.95 for BBB impairment, and serum IL-16, VEGF-D, IL-15, and other variables generated an AUC of 0.92 for BBB impairment.” “BBB breakdown is associated with more rapid cognitive decline. Inflammatory mechanisms, including cell adhesion, neutrophil migration, lipid metabolism, and angiogenesis may be implicated.”