Premium
P4‐301: REGION‐LEVEL RELATIONSHIPS BETWEEN TAU, AMYLOID, HYPOMETABOLISM AND ATROPHY IN ATYPICAL ALZHEIMER'S DISEASE
Author(s) -
Sintini Irene,
Schwarz Christopher G.,
Martin Peter R.,
Graff-Radford Jonathan,
Machulda Mary M.,
Senjem Matthew L.,
Spychalla Anthony J.,
Drubach Daniel A.,
Lowe Val J.,
Jack Clifford R.,
Josephs Keith A.,
Whitwell Jennifer L.
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.07.124
Subject(s) - posterior cortical atrophy , precuneus , atrophy , pittsburgh compound b , voxel , primary progressive aphasia , neuroimaging , psychology , medicine , alzheimer's disease , pathology , nuclear medicine , neuroscience , dementia , frontotemporal dementia , radiology , disease , cognition
Figure 2. First canonical dimensions from sparse canonical correlation analyses: tau SUVR versus FDG SUVR (a) and Ab SUVR (b). Colors represent the canonical weights found by SCCA for the ROI that contributed to the first canonical dimensions. ROI associated to weights equal to zero are left transparent. Irene Sintini, Christopher G. Schwarz, Peter R. Martin, Jonathan GraffRadford, Mary M. Machulda, Matthew L. Senjem, Anthony J. Spychalla, Daniel A. Drubach, Val J. Lowe, Clifford R. Jack, Jr., Keith A. Josephs, Jennifer L. Whitwell, Mayo Clinic, Rochester, MN, USA. Contact e-mail: Sintini.Irene@mayo.edu