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P2‐306: WHITE MATTER CHANGES IN VARIOUS STAGE OF ALZHEIMER'S DISEASE
Author(s) -
Tsai Tung-Kang,
Huang Ling-Chun,
Yang Yuan-Han
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.996
Subject(s) - clinical dementia rating , medicine , dementia , apolipoprotein e , leukoaraiosis , logistic regression , disease , stage (stratigraphy) , cognitive decline , white matter , diabetes mellitus , cardiology , psychology , endocrinology , magnetic resonance imaging , biology , paleontology , radiology
Preoperative complications like delirium were not significantly different among the normal and the ‘patients with cognitive impairment (CI)’ (P1⁄40.09). The incidence of bedsores (P1⁄40.08), postural hypotension (P1⁄40.06) and hospital acquired pneumonia (P1⁄40.06) was not significantly different among the normal and the CI patients. But complications like urinary tract infection (P<0.001), deep vein thrombosis (P1⁄40.03) and pulmonary embolism (P1⁄40.01) were significantly higher among the CI patients. Similarly, hospital stay was longer in the CI group in comparison to the normal ones (P1⁄40.03). A significantly higher number of CI patients died within their hospital stay. In addition to that, mortality at 30th day was significantly higher in the CI group. Conclusions:The overall outcomes of hip fracture surgery were significantly poorer in the patients with cognitive impairment in comparison to the cognitively normal ones. All the elderly patients should be assessed for cognition before hip fracture surgeries. Prompt preparedness for the possible complications related to surgery is essential and complications should be managed accordingly.