P2‐289: CLINICAL PROFILE OF BEHAVIORAL AND PSYCHOLOGICAL SYMPTOMS IN ELDERLY WITH DEMENTIA

method. dT2Awas strongly correlated with Clinical Dementia Rating Scale “sum of boxes” (CDR-SB) in both studies, and dT2A exhibited a high Area Under the Receiver Operating Characteristic Curve (AUC) for the discrimination of Alzheimer’s Disease (AD) v. Normal Controls (NC) in both studies. As a demonstration of d’s indifference to its indicators, we modeled alternative homologs with fewer cognitive indicators. Homologs lacking any combination of Logical Memory II, Boston Naming and /or Animal Naming performed similarly to the full dT2A homolog. Conclusions: This is the twelfth d homolog validated to date. Regardless of its indicators, d correlates strongly with CDR-SB and accurately diagnoses dementia, across diagnoses and multiple cohorts. This implicates g as dementia’s essential cognitive impairment.