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P2‐080: SUVN‐502: A PURE 5‐HT 6 ANTAGONIST AMELIORATES MEMORY DEFICIT IN TWO DIFFERENTIALLY CHALLENGED SOCIAL RECOGNITION TASKS
Author(s) -
Nirogi Ramakrishna,
Venkata Ramalingayya Grandhi,
Ganuga Narender,
Talakanti Hemasundar Reddy,
Jayarajan Pradeep
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.765
Subject(s) - juvenile , psychology , task (project management) , antagonist , discriminative model , cognition , developmental psychology , neuroscience , medicine , receptor , biology , computer science , artificial intelligence , genetics , management , economics
2,3). BP negatively correlated with distance traveled (OFT) in DSS (R1⁄4-0.54, p1⁄40.01). 12-mo DSS demonstrated impairment in identifying the location of the invisible platform in a MWM (Table). Conclusions: Observable behavior in aged hypertensive DSS may reflect differences in sympathetic activation, anxiety, hyperactivity, or acceleration of memory impairment; the change in motor function, however, is delayed in DSS vs. SD. Age-associated development of the impairments in several memory components along