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P1‐638: THE ASSOCIATION OF PHYSICAL ACTIVITY WITH COGNITIVE IMPAIRMENT
Author(s) -
Hindosh Ziad,
Stipho Faissal,
Gomez Tirambulo Coco Victoria,
Mills Caroline Sutherland,
Sween Alexandra,
Golden Todd Rabkin,
Mohler Jane,
Toosizadeh Nima
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.650
Subject(s) - montreal cognitive assessment , cognition , medicine , aerobic exercise , gerontology , physical activity , cognitive impairment , association (psychology) , physical therapy , metabolic equivalent , cohort , psychology , psychiatry , psychotherapist
Background:Physical activity (PA) and cognitive performance are associated, especially among the elderly. Although the role of PA in cognitive impairments is unclear, recent studies suggest it facilitates neuroplasticity and cognitive function. We investigated the association of PA on cognitive health as measured by the validated, modified Minnesota Leisure-time Physical Activity Questionnaire and the Montreal Cognitive Assessment (MoCA) among older adults. Methods: We performed the MoCA and administered the Fried Frailty assessment in the NIH-funded Arizona Frailty Cohort of community-dwelling adults aged>65 years. TheMinnesota Leisure-time Physical Activity Questionnaire was used to assess physical activity, using the guidelines for moderate-intense activities and beneficial exercise set by the Centers for Disease Control and Prevention (CDC). Moderate-intense activities including walking, moderately strenuous household chores, gardening, biking, exercise cycle, aerobic exercise, general exercise, and dancing were assessed. The total minutes of PA within a two-week duration was calculated for each participant, and the total minutes of PA > 300 minutes was used to identify beneficial physical activity, as defined by the CDC physical activity guidelines. AMoCa cut-off score<25 (range: 0-30) was used to identify participants with mild cognitive impairments. Using total minutes of PA as the independent variable and MoCA scores as the dependent variable, a linear regression (adjusted with age, gender, and BMI) was used to assess the association between PA and cognition. Results:Eighty-five older adults (mean age: 79.3+7.7, range: 65-95), 58% female were assessed, among which 43 (51%, mean age: 81.5+7.7) were cognitively impaired. Overall, cognitive score and physical activity were significantly associated (p<0.035, adjusted for age, gender, and BMI). This association differed between males (p<0.003) and females (p>0.54). Conclusions: Increased physical activity was associated with the absence of cognitive impairment. An understanding of this relationship between physical activity and cognition can help inform clinical screening practices, management, and interventions. Older adults with decreased physical activity are at an increased risk of having cognitive impairment, and should be routinely screened for cognitive impairment in primary care.