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P1‐634: SLEEP PARAMETERS MAY PREDICT FUTURE COGNITIVE DECLINE: A PROSPECTIVE NON‐DEMENTED ELDERLY COHORT STUDY
Author(s) -
Suh Seung Wan,
Han Ji Won,
Lee Ju Ri,
Byun Seonjeong,
Lee Kyoung Hwan,
Hong Jong Woo,
Kwak Kyung Phil,
Kim Bong-Jo,
Kim Shin Gyeom,
Kim Jeong Lan,
Kim Tae Hui,
Ryu Seung-ho,
Moon Seok Woo,
Park Joon Hyuk,
Seo Ji Young,
Youn Jong Chul,
Lee Dong Young,
Lee Dong Woo,
Lee Seok Bum,
Lee Jung Jae,
Jhoo JinHyeong,
Kim Ki Woong
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.646
Subject(s) - cognitive decline , sleep onset latency , sleep (system call) , medicine , cohort , pittsburgh sleep quality index , cognition , prospective cohort study , gerontology , cohort study , odds ratio , geriatric depression scale , sleep debt , effects of sleep deprivation on cognitive performance , psychology , dementia , psychiatry , sleep disorder , disease , sleep quality , computer science , operating system , depressive symptoms
Background:Increased sleep disturbances occur with increasing age (M. Ohayon, 2002), and sleep disturbances are associated with poor cognitive outcomes, including dementia (Spira et al, 2014). Women are more likely to have sleep problems and are at an even greater risk of insomnia symptoms with increasing age (B. Zhang et al, 2006), and women are twice as likely as men to develop Alzheimer’s disease (Alzheimer’s Fact Sheet, 2017). Finally, older adults are more likely to experience falls with increasing age, and worldwide, a third of those 65 and older experience falls at least once per year (World Health Organization, 2007). This paper examines the relationship between fall related worry and insomnia symptoms which could be modifiable risk factors for Alzheimer’s disease. Methods: Using data from 7,075 survey respondents in 2012 of the National Health and Aging Trends Study, we examined the association between fall-related worry and insomnia symptoms in a nationally representative sample of Medicare beneficiaries aged 65 and older. Logistic regression models were developed to examine the relationship between fall-related worry and insomnia symptoms in older adults, controlling for common covariates. Results:Results indicated fall-related worry was associated with a higher odds of insomnia symptoms, after adjusting for race, age, gender, and education (Model 1) (OR1⁄4 2.20, 95% CI: 1.88, 2.59), plus number of health conditions (Model 2) (OR1⁄4 1.87, 95% CI: 1.58, 2.20), plus anxiety and depression (Model 3) (OR1⁄4 1.42, 95% CI: 1.20, 1.70), p < 0.001 for all three models. Conclusions:These findings indicate that after accounting for potential confounders, older adults who worry about falling are more likely to experience insomnia symptoms than those who do not worry about falling. Fall-related worry and insomnia symptoms are both modifiable risk factors, and future studies might be wellsuited to examine interventions in which to reduce the risk of both, hence possibly reducing the risk of cognitive decline and Alzheimer’s disease.