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P1‐460: INTERRELATION OF IN‐VIVO STRUCTURAL AND MOLECULAR IMAGING MARKERS OF CHOLINERGIC SYSTEM DEGENERATION IN PD‐RELATED COGNITIVE DECLINE
Author(s) -
Grothe Michel J.,
Muller Martijn,
Álvarez Elvira,
Bohnen Nicolaas I.,
Teipel Stefan J.
Publication year - 2018
Publication title -
alzheimer's and dementia
Language(s) - Italian
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2018.06.470
Subject(s) - cholinergic , basal forebrain , neuroscience , acetylcholinesterase , cholinergic neuron , psychology , medicine , cognition , neuroimaging , pathology , biology , biochemistry , enzyme
Memory, 60-month change (95% CI) -0.077 (-0.47, 0.31) 0.58 (-0.09, 1.24) 0.37 (-0.51, 1.24) -1.91 (-4.59, 0.76) 0.15 Language, 60-month change (95% CI) -0.84 (-1.29, -0.39) -0.10 (-0.86, 0.65) -0.40 (-1.45, 0.64) -4.87 (-7.81, -1.94) 0.013 Visuospatial, 60-month change (95% CI) -1.60 (-2.26, -0.93) 1.53 (0.38, 2.68) -3.11 (-4.66, -1.56) -3.88 (-8.46, 0.71) <0.001 Executive, 60-month change (95% CI) 1.68 (1.00, 2.37) 0.25 (-0.92, 1.41) 1.21 (-0.39, 2.80) 3.61 (-1.45, 8.67) 0.16 Poster Presentations: Sunday, July 22, 2018 P496